With the change of lifestyle, more and more patients with coronary artery disease are admitted to the hospital. And a significant number of patients have coronary angiograms done and coronary stents implanted. Do you know enough about coronary stents? First, let’s look at what coronary artery disease is. Coronary heart disease is a heart disease caused by atherosclerosis of the coronary arteries, resulting in narrowing or occlusion of the lumen of the arteries, which leads to myocardial ischemia, hypoxia or necrosis. When coronary heart disease progresses to a certain degree, the stenosis of blood vessels is more serious, or the plaque in the coronary arteries is extremely unstable, or even the blood vessels are acutely occluded, and the effect of medication is unsatisfactory, the implantation of coronary stents may be required. The history of coronary intervention dates back to September 16, 1977. A French professor performed the first coronary balloon dilatation at the University Hospital in Zurich, Switzerland. The balloon was used to open up the narrowed blood vessel and squeeze the plaque that had been protruding into the lumen outward. This treatment improves coronary blood supply in the short term, but follow-up reveals that the stenosis quickly elastically retracts, with a restenosis rate of more than half with balloon dilatation alone. To avoid this elastic retraction, stents were created, which support the narrowed vessel through a skeletal structure. Coronary stents have evolved considerably since their inception. It started with bare metal stents, then drug-coated stents appeared, and currently there are biodegradable stents on the market. Since 1993, bare metal stents were used in the clinic, but it was found that endothelial hyperplasia of blood vessels within the stent would cause restenosis of the stent. After that, people coated the surface of the stent with anti-endothelial hyperplasia drugs, i.e. drug-coated stents. The second generation of drug-coated stents, which we are now mainly using in the clinic, has improved the stent coating. Now the third generation of biodegradable stents has emerged, which can be completely dissolved over time. Biodegradable stents are now available in China. For some patients with special coronary lesions, there is also drug balloon technology, which means that the drug is coated on the outside of the coronary balloon, and after the balloon is dilated, the drug is affixed to the intima of the blood vessel to play a role.