Generalized numbness and tingling should be treated with general treatment, medication or surgery for the disease, etc. Common diseases include central neuropathy, diabetes mellitus, drug intoxication, mental illness, and so on. 1. Central neuropathy: cerebral hemorrhage, cerebral infarction, encephalitis, etc., will lead to central neuropathy of the brain. Treatment includes mannitol dehydration to lower cranial pressure, surgery to remove hematoma, alteplase thrombolytic therapy, use of ganciclovir anti-virus, vancomycin anti-infection therapy. 2. Diabetes mellitus: Diabetes mellitus can lead to peripheral nerve dysfunction, such as spinal nerves, cerebral nerves, vegetative nerves, etc. In this case, we need to use metformin, acarbose, insulin to control blood glucose, and at the same time, we need to use pancreatic kininogenic enzyme, eparastat tablets, methylcobalamin, vitamin B12 and other medications to nourish the nerves. 3. Drug poisoning: drug poisoning can lead to chronic poisoning of the central nervous system, resulting in symptoms of generalized numbness and tingling. During acute attacks, the body should be cleared of drugs as soon as possible, and then use blood purification and other methods to promote the discharge of poisons. 4. Mental illness: depression, anxiety disorders and other diseases can cause mental anomalies, abnormal sensations such as generalized numbness and tingling, etc., you can use anti-anxiety, antidepressant drugs to relieve, such as haloperidol melittin tablets and other drugs. The whole body numbness and tingling should be timely medical treatment, identify the cause of the disease after targeted treatment, strictly comply with the doctor’s instructions to take medication.