When the body temperature exceeds 39 degrees Celsius or 40 degrees Celsius, the symptoms of heat stroke such as sweating shutdown, dizziness and headache, and mental disorders often occur, and respiratory failure can occur within a few hours in severe cases. The differential diagnosis of sweating shutdown: (a) generalized anhidrosis 1. congenital ectodermal dysplasia Patients often combine sebaceous gland, hair, nail, etc. with sebaceous duct dysplasia or deficiency. 2, systemic diseases caused by dry syndrome; urolithiasis; chronic nephritis; fluid edema; diabetes mellitus. (2) Restricted anhidrosis 1.Dermatological diseases There are ichthyosis; scleroderma; leprosy; radiation dermatitis; vitamin A deficiency. 2, neurological diseases such as transverse myelitis; poliomyelitis; spinal cord cavitation.