Low platelet specific volume is generally common in peripheral platelet reduction, aplastic anemia, acute leukemia, myelodysplasia, etc. can make the platelet specific volume low.
1. Aplastic anemia: it is because of various reasons that the hematopoietic function of bone marrow is reduced, and it is prone to anemia and infection.
2. Acute leukemia: it is the malignant proliferation of hematopoietic stem cells. Primitive cells and naive cells proliferate in large numbers during the onset of the disease, thus inhibiting normal hematopoiesis.
3. Myelodysplasia: Myelodysplastic syndrome is due to the lesion of bone marrow hematopoietic stem cells, abnormal proliferation, resulting in ineffective hematopoiesis. The main manifestation is peripheral blood cell reduction, and may develop into leukemia.
Generally a single platelet ratio decrease has no clinical significance, if there is platelet abnormality at the same time, you should go to the hospital as soon as possible to check and clarify the cause of the disease, so as not to delay the condition.