Drugs should be chosen according to the cause of high lymphocyte percentage. Common causes include physiological increase, pathological increase such as viral infection, blood disease, etc. Drugs involved in the treatment include antiviral drugs and chemotherapeutic drugs. 1. Physiological increase: Lymphocytes may increase in childhood, they are higher in the afternoon and evening than in the morning, and they may increase after a short period of light physical activity, which is physiological and does not require medication. 2. Pathological increase (1) Viral infections: usually caused by viral infections, such as influenza virus, measles virus, chickenpox virus, mumps virus, etc. Antiviral drugs such as ribavirin, oseltamivir phosphate, acyclovir, etc., can be taken for treatment. (2) Diseases such as leukemia and lymphoma can also cause an increase in the percentage of lymphocytes, which requires targeted treatment. Chemotherapy drugs such as methotrexate and dexamethasone are usually used for leukemia, and doxorubicin is used for lymphoma. High lymphocyte percentage can also be caused by other reasons, such as the recovery period of acute infectious diseases, tuberculosis infection, aplastic anemia, granulocytopenia, granulocyte deficiency, etc. It is recommended to go to the hospital in a timely manner to find out the cause of the disease and then targeted treatment. All of the above medications should be used under the guidance of a doctor, avoid self-medication.