Rabies immunoglobulin lasts for approximately 2 weeks. Rabies immunoglobulin is a passive immune agent, mainly used for localized infiltration at the site of injury, which directly neutralizes the rabies virus that has just entered the body and builds a first barrier to prevent the virus from spreading from the wound to the surrounding nerve tissue. This neutralizing antibody does not increase the level of antibodies in the peripheral circulation. This neutralizing antibody does not increase the level of antibody in the peripheral circulation. The increase in the level of antibody in the peripheral circulation is mainly due to the active immunoprotection that occurs after rabies vaccination. The effect of rabies immunoglobulin lasts about two weeks, and it takes about 1 to 2 weeks for the rabies vaccine to induce the body to produce antibodies. The blank zone before the production of protection induced by active immunization with rabies vaccine is called the period of high-risk infection, and rabies immunoglobulin can provide immune protection for this high-risk period. Application of rabies immunoglobulin is recommended to be done in regular hospitals.