The normal value of blood calcium is 9mdash;11 milligrams of calcium in 100 milliliters of blood, or 2.2mdash;2.7 millimolar concentration per liter of blood. The normal fluctuation of blood calcium is small, mainly because calcium is extremely important for maintaining many physiological functions in the body. Blood calcium ion testing can determine the likelihood of a variety of diseases. For example, in hyperparathyroidism, blood ionized calcium is higher than the normal range. So how is high calcium ions in the blood diagnosed? The following is a brief introduction. 1, serum calcium: high blood calcium is the most important biochemical index of the disease and has the most diagnostic value. If measured only once, only 1/2 patients present. There are many patients who need to repeat several laboratory tests in the same laboratory to be found. A blood calcium > 2.6 mmol/l is required to diagnose hypercalcemia. 2, bone and joint damage: generalized diffuse bone disease, mostly gravity-bearing bones, such as lower extremities, lumbar spine, plantar disease is most common and intensifies after activity. On physical examination, there may be pressure pain in the long bones, to the occurrence of spontaneous fractures, especially in the cystic lesion sites occurring mostly in the long bones, and occasionally in the mandible. Joint pain, which is caused by subchondral fracture or erosive arthritis, is very easy to be misdiagnosed as wind-like off. 3, neuropsychiatric lesions: when the blood calcium 3-4 when there are symptoms of mental weakness. 4 when the organic psychosis, delirium, delirium. Close to 5 when coma is unconscious. A few have headache, stroke, extravertebral lesions, paralysis, which may be related to intracranial calcification.