Melasma is a common pigmentation disorder with complex etiology, related to genetics, sun exposure, pregnancy, oral contraceptives, endocrine abnormalities, cosmetics and drugs. The pathological manifestations are mainly the increase of melanin in the skin mainly in the epidermis and the excessive melanin deposition in the skin caused by the hyperfunction of melanocytes. Why is it necessary to treat melasma with standardized, persistent and comprehensive treatment? In order to eliminate chloasma, Ms. Chen listened to the beauty salon’s advice to do “fast spot removal” beauty treatment, and the effect was so good that she went through the treatment. However, after a long time, she found that her chloasma not only recurred but also became more and more serious. Even the skin on other parts of her body was getting worse and worse, with pain in her face, small red rashes, and redness with fever occurring frequently. Finally, the doctor diagnosed that Ms. Chen’s skin was damaged by using some drugs or cosmetics containing keratin exfoliators that frequently exfoliated the skin’s stratum corneum, resulting in a damaged skin barrier. The skin itself secretes more melanin in order to restore its defense function, which makes melasma more serious. The cause of melasma is complex and contains many factors, so it is difficult to have a good effect by a single treatment alone. Moreover, there are a lot of non-existent treatments on the market, which not only cannot play a therapeutic role but also cause serious damage to the skin. Therefore, the treatment of melasma must be standardized in regular hospitals. The treatment of melasma is a complicated process that requires joint efforts and cooperation between doctors and patients, and the treatment process is time-consuming, labor-intensive and patient-intensive. Moreover, the chance of recurrence of melasma is very high, so it is very necessary to adhere to the treatment. 3.Comprehensive treatment The treatment of melasma should start from the cause of the disease and treat the symptoms. There are many treatment methods, such as laser, colored light, micro-needle, fruit acid, topical medicine, oral medicine, injection treatment and so on. A person with melasma is generally caused by a combination of many factors. So for different causes, different ways of treatment are needed. That’s why it is said that comprehensive treatment of melasma is very necessary. After the treatment, the daily maintenance of melasma is also very important. Treatment and daily maintenance of melasma can be said to be equally divided, and both hands must be grasped and both hands must be strong. Especially, many melasma patients have emotional problems such as anxiety, depression, low self-esteem, etc. These emotional problems will trigger insomnia and mental fluctuations, which are especially unfavorable to treatment. 1. Sun protection: It is crucial to do well in effective sun protection. Sunlight will definitely aggravate melasma, so it is necessary to do a good job of effective sun protection. 2.Reducing stimulation: The destruction of skin barrier and the occurrence of melasma are closely related. For useless care procedures can be simplified, streamline the skin care products of patients and use the correct cleaning method, which can accelerate the recovery of skin barrier and help a lot in the treatment of melasma. 3.Chinese patent medicines: Chinese patent medicines such as compound xinizhi granules, prozac pills and six-flavored dihuang pills can be given to patients according to the results of Chinese medicine dialectical treatment to assist treatment. 4.Dietary regulation: Try to consume less photosensitive food, medicinal food and medicinal tea have certain auxiliary effect on the improvement of melasma.