Symptoms of Yang depression and syncope (cold extremities due to poor circulation of Yang Qi) include lack of warmth in the hands and feet, abdominal pain, and heaviness in the lower part of the body due to diarrhea. Yang depression and syncope is mostly due to the external evil transmission of meridians into the interior, qi stagnation, can not be drained, resulting in yang qi internal depression, can not reach the end of the four, and see the hands and feet do not feel warm. Liver qi stagnation, irregular detachment and excretion, liver wood multiplied by spleen earth, can be seen in the epigastric (abdominal) pain or discharge under the weight of the symptoms. The treatment should be to dispel evils and relieve depression, and to regulate the qi. Four Rebellious San can be used with additional subtractions. Sihui San is composed of Chaihu, Paeonia lactiflora, Citrus aurantium dulcis, and licorice, which has the effect of dispersing the liver and regulating the spleen by penetrating the evil and relieving the depression. In the formula, Chai Hu enters the liver and gallbladder meridian, elevating Yang Qi, dredging the liver and relieving depression, and transmitting the evil out. Bai Shao converges Yin, nourishes Blood and softens the Liver (nourishes Blood and softens the Liver). Citrus aurantium regulates qi and resolves depression, drains heat and breaks up knots. Glycyrrhiza glabra harmonizes all medicines (harmonizes the medicinal properties of different herbs), benefits the spleen and harmonizes the middle. Adverse effects and contraindications of this drug are not known. If there is a need to use this drug, it is recommended to use it under the guidance of a professional physician, and not blindly self-medication.