Lateral ankle pain is also known as pain in the outer ankle, the pain in the outer ankle may be caused by physiological factors such as exercise strain, cold environmental stimulation, or it may be caused by pathologic factors such as lateral ankle ligament injury, arthritis, etc. The pain in the outer ankle can be caused by the physical causes of the pain. 1. Physiological reasons: people who often run, climb mountains and other physical exercise, due to the repeated activities of the ankle joint, may cause fatigue injury to the soft tissues around the ankle, resulting in aseptic inflammation and pain symptoms; cold environment leads to cold ankle joints, which may also lead to the above symptoms. 2. Pathological factors: when the exercise load exceeds the limit of the soft tissues around the ankle or when external force is exerted, it may cause injury or tear of the ligaments around the ankle, and the symptoms of lateral ankle pain may also appear; when arthritis occurs in the ankle joint due to various reasons, it may cause osteophytes and excessive wear and tear of the cartilage in the joint, and the above symptoms may also appear. The symptoms of lateral ankle pain alone may not be able to accurately determine the cause, but need to be combined with the characteristics of the medical history, other test results to make an accurate judgment, it is recommended to go to the hospital in a timely manner, under the guidance of the doctor standardized treatment.