Rosacea is rosacea, metronidazole can play the role of antibacterial, for rosacea inflammatory skin lesions have a certain efficacy. The etiology and pathogenesis of rosacea are still unclear, and it is thought to be related to genetics, abnormal neurovascular regulation, microbial infections, etc., in which the follicular helminth mite and local recurrent infections are one of the important factors in the development of this disease. Therefore, antibiotics are one of the main therapeutic drugs for rosacea, and topical metronidazole can resist follicle mites, and has a certain effect on the erythema and inflammatory lesions of rosacea. Antibiotics can produce drug resistance, need to pay attention to under the guidance of the doctor standardized use. For those who are allergic to metronidazole, other antibiotics such as doxycycline and minocycline can be used instead. If you have rosacea, it is recommended that you go to the hospital in time, and the medication should be used according to the doctor’s instructions.