There are five kinds of hard lumps in the breast: first, cystic hyperplasia, clinical manifestations of breast nodules, accompanied by breast swelling and pain, and the pain is mostly related to the menstrual cycle, when the symptoms are obvious, local hot compresses can be applied, and oral Xiaojin pill or prolotherapy, if drug treatment does not work, the nodules should be suspected of having cancerous potential, timely surgery. Secondly, fibroid tumor, which has no obvious clinical symptoms, can be palpated in the breast as a regular smooth lump with high mobility, and has the tendency of cancer, and should be actively operated once diagnosed. Thirdly, intraductal papilloma, which is insidious in onset, is often found with light blood-colored fluid on the underwear, and should be treated by surgery as early as possible. Fourthly, breast cancer, when the disease progresses to advanced stage, orange peel sign may appear due to the blockage of subcutaneous lymphatic vessels by cancer cells, which should be treated by early surgery and combined with chemotherapy if necessary. Fifthly, acute mastitis, which is an acute purulent infection of breast tissue, may cause breast swelling and pain with fluctuating lump formation, and should be treated with anti-infection, and abscess incision and drainage should be performed in time when symptoms worsen.