Non-stop hiccups, there are many reasons, such as gastritis, indigestion, gastrointestinal dysfunction, central nervous system diseases, etc. The treatment of hiccups include deep breathing, bending over to drink water, breath holding, stretching and pulling the tongue, etc. Physical therapy is ineffective when the application of medication such as omeprazole and baclofen. 1. Deep breathing: when eating, if hiccups occur, you can stop eating and take deep breaths repeatedly, which can often stop hiccups very quickly. 2. Bend over and drink water method: bend your waist 90°, and then drink hot water properly. As the stomach is very close to the diaphragm, it can have the effect of warming the diaphragm. Secondly, the internal organs will come into contact with the diaphragm and play a massaging role in order to eliminate the spasm. 3. Breath-holding method: After hiccups occur, you can hold your breath for about half a minute immediately, so that the diaphragm movement is affected to a certain extent to relieve the problem of hiccups. 4. Stretching the tongue: If hiccups persist for a long time, it is recommended to stretch the tongue outward to make the abdominal gas rise and inhibit the diaphragm activity to eliminate hiccups. 5. Medication: If the patient’s physical therapy is ineffective, medication can be applied, because gastrointestinal diseases are the most common cause of intractable hiccups, and diagnostic antacid treatment, such as omeprazole, can be applied to baclofen, metoclopramide and other drugs if omeprazole is ineffective. If the patient persistent hiccups do not relieve, should be timely to the hospital, clear hiccups cause, give targeted treatment, avoid self-medication.