Amlodipine benzenesulfonate with angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists and beta-blockers are effective, but the specific use of the drug should be subject to the guidance of the doctor. 1. Angiotensin-converting enzyme inhibitors: representative drugs include captopril, etc., which inhibit the formation of active angiotensin by inhibiting the conversion of angiotensin, and thus achieve the effect of lowering blood pressure by relaxing blood vessels. This kind of drugs and amlodipine benzenesulfonate have different mechanisms of action, and can offset each other’s potential adverse effects, which is a very good choice for pairing. 2. Angiotensin II receptor antagonist: the representative of this kind of drugs, such as valsartan, by antagonizing the action of the active angiotensin to make vasodilatation and then lower blood pressure. Similarly, these drugs and amlodipine benzenesulfonate have different mechanisms of action and can be used in combination with each other. 3. β-blockers: common drugs are bisoprolol, metoprolol, etc. Because β-blockers can relieve myocardial hypoxia through negative heart rate in addition to lowering blood pressure, they are the first choice of drugs for hypertensive patients with tachyarrhythmia. It is recommended that the antihypertensive drug regimen be adjusted under the guidance of a physician.