Patients with epilepsy should take antiepileptic drugs regularly. During the period of taking antiepileptic drugs, the following drugs should be used with caution or prohibited for patients with epilepsy in order to avoid seizures. 1, quinolones: a history of epilepsy should be used with caution quinolones, including norfloxacin, enoxacin, ciprofloxacin, ofloxacin, etc.. Because such drugs can cause toxic side effects in the central nervous system. 2, glucocorticoids: including cortisone acetate, hydrocortisone acetate, prednisone acetate, dexamethasone, etc. This type of drugs can induce psychiatric symptoms and seizures, epilepsy patients with caution or do not use such drugs. 3, isoniazid: too large a dose of isoniazid or a long period of time, can cause adverse reactions in the nervous system, inducing convulsions, so should be used with caution. 4, tricyclic antidepressants: including promethazine, amitriptyline, meptyline, Ritalin, etc.. These drugs have a certain excitatory effect and can cause convulsions or induce seizures when applied in large doses or for a long time. Promethazine is prohibited in patients with epilepsy, and other antidepressants should be used with caution. 5, anticholinesterase drugs: neostigmine bromide, neostigmine methosulfate, are reversible anticholinesterase drugs, which can cause muscle tremors and induce seizures, so they should be disabled.