Exercise angina requires medications such as aspirin, atorvastatin, and isosorbide nitrate. Exercise angina indicates that there is a narrowing of the coronary arteries, due to the increased demand for oxygen during exercise, the blood supply to the heart itself can not be increased in a timely manner resulting in hypoxia, inducing angina attacks. Aspirin is an antiplatelet drug that can inhibit platelet aggregation and improve blood supply to the coronary arteries. Atorvastatin is a plaque-suppressing and lipid-lowering drug that can slow down the progression of coronary arteries, and is a basic drug for coronary heart disease. Isosorbide nitrate can dilate the coronary arteries, increase the blood supply of coronary arteries, can significantly improve the patient’s symptoms. Patients with fast heart rate can also take metoprolol orally to control the heart rate while being able to reduce myocardial oxygen consumption. Exercise angina patients should promptly go to the hospital, under the guidance of physicians to give targeted treatment.