There are many reasons for stomach pain when pressing the stomach: first, there may be digestive system diseases, such as acute cholecystitis, acute gastroenteritis or diffuse peritonitis, which can cause pain when pressing the stomach. Secondly, it may be due to urological diseases, such as ureteral stenosis or ureteral stones, which can also cause significant reflex pain when pressing the stomach. Again, it may be caused by general surgery diseases, such as acute appendicitis, acute diffuse peritonitis, septic perforated appendicitis, or severe gastrointestinal perforation, which may also cause significant pain when pressing on the stomach. Finally, mainly in women, women suffering from tubal ectopic pregnancy or acute pelvic inflammatory disease or adnexitis may also experience pain in the stomach after pressing on the abdomen.