Coarse skin follicular pores, mainly due to endocrine disorders resulting in excessive secretion of androgens, causing the follicular sebaceous glands to secrete too much oil, which is a barrier to the excretion of oil leading to bacterial growth, resulting in the enlargement of the pores. In the treatment of the need to keep the skin clean, you can apply sulfur soap to wash the face, external moisturizing milk, moisturizing cream. In case of mild enlarged pores, a mixture of Adapalene gel and Urea Vitamin E cream can be applied externally, as well as topical Centella Asiatica cream ointment. In addition, if the enlarged pores are obvious and accompanied by a large number of blackheads, then you can go to the regular three hospitals for medical treatment, such as if acid peeling, photorejuvenation, laser, as well as gold micro-needle, ionic introduction of the treatment. During the treatment period, you need to avoid spicy, stimulating food, avoid alcohol, while reducing the intake of fried and sweet food. Pay attention to rest, reduce the late night, at the same time, it is recommended that patients with large skin pores to regular hospitals, looking for professional dermatologists for clinical treatment.