The gallbladder wall roughness does not necessarily require oral medication, it is an abnormal manifestation of gallbladder ultrasound, the details are as follows: 1, if there is no liver lesion, no gallbladder stones or polyps, and the patient has no clinical symptoms, the simple gallbladder wall roughness can be observed without oral medication, regular ultrasound follow-up can be, daily life should pay attention to low-fat diet, regular diet, and eat breakfast. 2, if If there are multiple stones in the gallbladder and the patient has recurrent pain in the right upper abdomen, the patient should be alert to the possibility of calculous cholecystitis. For recurrent stone cholecystitis, it is clinically recommended to remove the gallbladder surgically, laparoscopic cholecystectomy is preferred, and drug treatment is only treating the symptoms but not the root cause, and cannot fundamentally relieve the symptoms. 3. For example, if the virus replication is active in hepatitis B and C, then it is necessary to apply antiviral drugs for oral treatment.