Diabetic patients with poor glycemic control will gradually develop diabetic neuropathy with the following pathogenesis: 1) abnormal glucose metabolism; 2) abnormal fat metabolism; 3) abnormal protein metabolism. The abnormal metabolism will produce some excessive toxic products, and these toxic products have damage to nerve cells. In addition, the immunity of patients with poor blood glucose control is reduced, and there is also a lack of B vitamins, which can also cause nerve cell destruction. In patients with high blood glucose, the blood vessels in the body are damaged and the blood supply is poor, causing malnutrition of nerve cells. When diabetic patients develop diabetic neuropathy, they should control blood sugar as soon as possible, as well as add some nerve-nourishing drugs, along with diet and exercise, to make the symptoms disappear as soon as possible.