Dry skin on the palms of the hands may be caused by dry environment, physiological factors such as over-cleaning, or considered to be caused by dry eczema, psoriasis and other diseases. 1. Physiological factors: Physiological factors such as a dry environment, excessive cleaning, and reduced sweating at the palms of the hands may cause loss of moisture in the skin of the palms of the hands, resulting in the phenomenon of dry skin in the palms of the hands. 2. Dry eczema: dry eczema is caused by excessive water loss on the skin surface, reduced oil secretion, excessive washing, high water temperature, chronic ultraviolet damage and other factors. Patients will mostly have dry skin, fine cracks, itching, cracked skin or oozing blood, etc. If it occurs in the palms of the hands, it can be manifested as dry skin of the palms. 3. Psoriasis: Heredity, decreased immunity, excessive pressure, obesity, smoking, trauma and other factors may induce psoriasis. It is mostly manifested as translucent film and red papules on the skin surface, accompanied by silvery-white scales, etc., and may be characterized by dry skin on the palms of the hands. Patients with dry skin on the palms are advised to go to the hospital and under the guidance of the doctor, undergo relevant examinations to clarify the cause of the disease and treat the symptoms.