When patients appear glans and foreskin itching with red bumps, it may be caused by allergic skin disease, foreskin glansitis, condyloma acuminatum and other diseases, patients can improve their condition through general treatment, medication, surgical treatment and other ways. 1. Allergic dermatosis: patients should avoid contact with easily sensitized and irritating foods, such as fish, shrimp, strong tea, coffee, alcohol, etc. Antihistamines, such as benadryl, loratadine, etc., and anti-leukotrienes, such as zalustat and montelukast, etc., can also be used topically. You can also use local topical drugs, such as boric acid solution, aluminum acetate, etc. to improve the condition. 2. glans penis: glans penis patients can follow the doctor’s instructions to use antibiotics, such as amoxicillin, cefixime, ofloxacin, etc., or antifungal drugs, such as itraconazole, fluconazole, etc., and if necessary, can also be used to use glucocorticosteroid topical medications, such as budesonide ointment, hydrocortisone ointment and so on. 3. acromegaly: acromegaly patients can use imiquimod cream, fluorouracil cream and other drugs for local treatment under the guidance of the doctor. Patients can also undergo surgical treatment through high-frequency electrosurgery, shearing and scraping to improve symptoms such as red bumps.