The difference between gastric smooth muscle tumor and gastric mesenchymal tumor mainly lies in the different causes, different treatment methods and different severity of the disease. 1. Different causes: gastric smooth muscle tumor may be caused by genetic factors, mainly through genetic inheritance, some patients are caused by endocrine abnormality and long-term cold; while the cause of gastric mesenchymal stromal tumor may be caused by gene mutation or environmental interference. 2. Different treatment methods: when gastric smooth muscle tumor is detected, timely surgical resection is generally required, and those who have gastrointestinal bleeding need timely hemostasis or blood transfusion treatment; regarding gastric mesenchymal tumor, surgical treatment is the best, and imatinib should be used instead of treatment according to individual differences before surgery, and then adjuvant treatment is carried out after surgery. 3. The severity of the disease is different: gastric smooth muscle tumor grows slowly, but the larger tumors are not treated in time, which may cause upper gastrointestinal hemorrhage and easy to cause shock; gastric mesenchymal tumors untreated may develop into malignant tumors, and the survival rate of the disease will be affected once it recurs and metastasizes. The difference between gastric smooth muscle tumor and gastric mesenchymal stromal tumor mainly has the above points, in addition, the related symptoms and complications of the two are also different. If you want to accurately identify them, it is recommended to consult a doctor in time, and then analyze them based on imaging and laboratory tests.