In vitro fertilization-embryo transfer technique (commonly known as IVF) is not recommended during the onset of seminal vesiculitis as it may affect the quality of the fetus, and is recommended to be performed after the disease is fully cured. In vitro fertilization (IVF) is a procedure that uses artificial methods to fertilize egg cells and sperm outside of the body for early embryonic development, and then transfers them to the mother’s uterus to develop and give birth to a baby. Seminal vesiculitis is a relatively common infectious disease of the male reproductive system, the cause of which is mostly due to infection by pathogenic bacteria such as Escherichia coli, Klebsiella, Pseudomonas aeruginosa, etc. The patient will suffer from ejaculatory pain, frequent urination, bloody semen and other symptoms. Since seminal vesiculitis may affect the quality of sperm, in vitro fertilization-embryo transfer technique is not recommended during the onset of the disease. In addition, patients with vesiculitis will apply some drugs for treatment during the treatment period, which may also affect the quality of sperms and is not favorable to eugenics. For patients with vesiculitis, they should go to regular hospitals in time and standardize the treatment under the guidance of doctors to avoid delaying the condition. After curing, then evaluate and carry out in vitro fertilization-embryo transfer technique.