A 0.6*0.5cm ground glass nodule is a relatively small nodule, but whether it is serious or not depends on the nature of the nodule. If it is a benign nodule, it is usually not serious, while a malignant nodule is more serious. If 0.6*0.5cm ground glass nodule belongs to benign nodule, it is generally not serious, for example, ground glass nodule caused by pneumonia, tuberculosis and other diseases, this type of nodule can be gradually shrunk and returned to normal through timely treatment. If it belongs to interstitial lung disease, multiple pulmonary fibrosis and other causes of ground glass nodules, the condition is relatively serious, will affect the patient’s normal respiratory function, it is recommended to follow the doctor’s instructions for treatment in a timely manner, through timely treatment of the condition can also be controlled. If the 0.6*0.5cm ground-glass nodule is malignant nodule, such as squamous lung cancer, lung adenocarcinoma, the condition is more serious, and it should be resected early and timely, in order to prolong the survival time of patients and improve the quality of life. In order to analyze the nature of the nodule as soon as possible, puncture biopsy of the nodule can be done if necessary, and regular treatment can be chosen to control the progression of the disease with the result of puncture.