Women’s lower body leukoplakia mainly refers to vulvar leukoplakia, which can be treated by medication, physical therapy and surgery. The related people should consult the doctor in time and accept regular treatment actively. 1. Drug treatment. Drugs need to be chosen according to the type of vulvar leukoplakia, and all drugs need to be used under the guidance of doctors. (1) Vulvar chronic simple moss medication. This type of people, mainly external glucocorticoid-based, play a role in controlling itching and relieving symptoms, such as tretinoin ointment, hydrocortisone ointment and so on. (2) Vulvar sclerotic moss medication. Including topical glucocorticosteroids, such as beclomethasone propionate, etc.; topical calcium-modulated phosphatase inhibitors, such as tacrolimus, etc., which can control the symptoms of itching; oral retinoids, such as retinoic acid, etc., which can delay the progress of the disease. 2. Physical therapy. That is, the lesion localized use of physical therapy, including carbon dioxide fractional laser, focused ultrasound, etc., can relieve itching, improve local blood circulation and so on. 3. Surgery. Currently, it is seldom used. For people with severe condition and ineffective non-surgical treatment, they can choose vulvectomy; for people with narrow vaginal opening and scarring of labia, they can choose vulvoplasty to repair the local adhesion scar.