Retroperitoneal lymph node metastasis of esophageal cancer can be treated with stereotactic radiotherapy, peritoneal thermal perfusion therapy and high intensity focused ultrasound therapy. 1. Stereotactic radiotherapy: stereotactic radiotherapy has certain therapeutic effect on retroperitoneal lymph node metastasis, but it can only be used as an auxiliary treatment. 2. Intraperitoneal hyperthermia: Intraperitoneal hyperthermia is a safe treatment technique, which can make the drug concentration in the peritoneal cavity 10 times higher than that of the systemic drug, but it has limited therapeutic effect on large retroperitoneal lymph nodes. 3. High-intensity focused ultrasound therapy: High-intensity focused ultrasound therapy is a non-invasive therapeutic technology, which gathers ultrasound waves in the tumor foci in vivo, causing tumor cells to undergo coagulative necrosis without damaging the surrounding tissues, which has a better effect on the treatment in the near future. Patients with esophageal malignant tumors who have retroperitoneal lymph node metastasis should go to regular hospitals in time to determine the specific treatment plan under the guidance of the doctor, and actively cooperate with the treatment to avoid the deterioration of the condition.