Many brown spots at the ankle may be due to post-inflammatory hyperpigmentation, pigmented nevus, flat warts and other factors, you can choose the general treatment, drug treatment and physical therapy and other methods. 1. Post-inflammatory hyperpigmentation: when the patient has local post-inflammatory hyperpigmentation, there will be many local brown spots, generally can be recovered on their own, but also can be used externally hydroquinone cream, arbutin, etc. to accelerate the recovery. 2. pigmented nevus: ankle long a lot of brown spots do not exclude the possibility of pigmented nevus, if you feel the impact of aesthetic, you can follow the doctor’s instructions to choose carbon dioxide laser and other physical methods to get rid of. 3. flat warts: due to human papilloma virus infection caused by flat warts, may also be manifested in the ankle part of the growth of many brown spots, can be in the doctor’s guidance to choose the way of liquid nitrogen freezing treatment, so as to remove the local warts. The actual warts can be removed by means of liquid nitrogen freezing underneath the doctor’s supervision. The above drugs and operations should be carried out under the guidance of a doctor.