Drinking glucose in large quantities on a regular basis will make you fat, drinking it once in a while will not. Glucose is the main energy substance of human body, providing energy for human activity. If you usually drink a lot of glucose, too much glucose intake, can not be fully utilized, the remaining glucose will be converted to fat storage, so it will get fat. If you drink occasionally, or often drink a small amount of some, will be metabolized by the body to produce energy, and will not be stored as fat, so it will not cause obesity. Any food need to eat in moderation, often drink a lot of glucose may also increase the burden on the pancreas, oral cleaning is not timely will cause dental caries and so on. Therefore, usually drink glucose occasionally or in moderation, will not cause obesity.