Thalassemia is hereditary, it is a genetic disorder that has a certain chance of being passed on to offspring. Thalassemia, also known as thalassemia, is a kind of hereditary hemolytic anemia caused by the mutation or deletion of the gene for the thalassemia peptide chain of hemoglobin, resulting in the reduced synthesis of the thalassemia peptide chain or its complete absence, and it is one of the most common single-gene hereditary diseases. If both parents are carriers of the thalassemia gene or are thalassemia patients, the probability of the offspring suffering from the disease will be greatly increased. It is recommended that both parents should undergo premarital testing and prenatal genetic diagnosis of the fetus, and consult with relevant specialists for evaluation to avoid the birth of an affected child.