Lumbar spine fracture 50 days out of bed walking knee pain, you can strengthen the functional exercise, physical therapy, oral medication for treatment. 1. Strengthening functional exercise: knee pain occurs when walking out of bed after 50 days of lumbar spine fracture, which is related to the wasteful atrophy of the muscles and ligaments around the joints after a long time of lying in bed. Before getting out of bed, you can carry out functional exercises such as knee flexion and hip flexion, straight leg raising, etc., to promote the functional recovery of muscles and ligaments around the joints. 2. Physical therapy: you can also use hot compresses, massage, electric baking and other physical therapy treatments for the knee joint, and you can also wear knee pads to strengthen the protection. 3. Oral medication: For obvious pain, you can also take anti-inflammatory and analgesic drugs for pain relief, such as diclofenac sodium, celecoxib and so on. If the lumbar vertebrae fracture 50 days of walking in bed with knee pain, it is recommended that the patient go to the hospital to improve the examination, accept the formal treatment.