The dosage of ursodeoxycholic acid in a few tablets is not clearly defined and is related to the therapeutic purpose, the patient’s body weight, the drug specification and other factors. Ursodeoxycholic acid can inhibit the secretion of cholesterol into the bile and the reabsorption of cholesterol in the intestinal tract, and reduce the concentration of cholesterol in the bile, and is commonly used in the treatment of cholesterol gallstones (which can be penetrated by X-rays, and have normal contractile function of gallbladder), cholestatic liver disease, and cholestatic reflux gastritis in the clinic. When used for the treatment of cholesterol gallstones and cholestatic liver disease, 8~10mg/kg per day is usually required, which is multiplied by the body weight to get the total amount to be taken per day, and then divided by the specification of the drug (i.e., the content of the drug in each tablet) to get the number of tablets to be taken per day, and half of the tablets are usually taken in the morning and half in the evening during the meals respectively. The course of treatment is generally 6~24 months, treatment needs to be carried out every 6 months ultrasound or X-ray examination, to observe the change of stone size, if the stone does not become smaller after 12 months of taking the patient, should stop taking the drug. Used in the treatment of bile reflux gastritis, each time the dosage of 250mg, divided by the specifications of the drug, you can get the number of tablets need to be taken, once a day at bedtime, the course of treatment is generally 10 ~ 14 days. However, ursodeoxycholic acid may cause diarrhea, abdominal pain, skin rash and other adverse reactions when taking it. It should be contraindicated in patients with acute cholecystitis and cholangitis, biliary obstruction, abnormal gallbladder contractile function, and should be used with caution in pregnant women and lactating women. Ursodeoxycholic acid should be taken in advance to consult a doctor, strictly according to the doctor’s instructions, not self-medication, so as not to delay or even aggravate the condition.