Whether hepatic cysts 48mmx30mm need treatment should be decided according to whether the patient has clinical symptoms, cyst site, nature and other factors, symptomatic and malignant tendency should be treated in a timely manner, asymptomatic and without malignant tendency can continue to observe. The pathogenesis of hepatic cysts is unclear. Since hepatic cysts generally do not have a tendency to malignant transformation, it is currently advocated that patients with a diameter of less than 5cm and no symptoms can be followed up for observation. For patients with larger cysts or those with compression symptoms or complications such as bleeding and infection, treatment modalities such as puncture and drainage, sclerosing agent injection and laparoscopic open drainage can be adopted according to the location, nature and age of the cysts. For liver cysts of 48mmx30mm, if the patient has no obvious clinical symptoms, the cyst has no tendency of malignant transformation, and the cyst does not compress the surrounding tissues and organs, the patient can continue to follow up and observe, and no treatment is required for the time being. If the patient has symptoms such as abdominal pain, abdominal distension, or if the cyst has a tendency to malignant transformation, it should be treated promptly. Therefore, patients with liver cysts of 48mmx30mm should go to the hospital in time and under the guidance of the doctor for regular treatment.