The main treatments for uncomfortable sickness and vomiting are etiologic treatment and symptomatic treatment, such as medication and surgical treatment, etc., which should be carried out under the guidance of doctors. 1. Etiological treatment: It is recommended to clarify the cause of the disease under the guidance of the doctor and carry out treatment. For example, if the patient is vomiting caused by acute gastroenteritis, water, electrolyte and acid-base balance should be maintained, anti-infection, commonly used drugs are levofloxacin, norfloxacin and other anti-infective drugs, and if the patient is dehydrated, he should also take oral or intravenous rehydration. If the patient is vomiting caused by acute appendicitis, surgical treatment should be taken. 2. Symptomatic treatment: clinically under the guidance of the doctor to take medication, commonly used drugs are antihistamines such as benadryl, chlorpromazine and other phenothiazine drugs, metoclopramide and other benzamides, ondansetron and other selective 5-hydroxytryptamine receptor antagonists, which can play a different degree of antiemetic effect. In short, sick and difficult to vomit should promptly seek medical attention to clarify the cause of the disease, under the guidance of the doctor for treatment, to avoid serious consequences.