You need to stop taking eplazole for at least 2 weeks before doing a C13 or C14 breath test for the results to be accurate. Eprazole is a proton pump inhibitor that is used to inhibit gastric acid secretion and is indicated for the treatment of duodenal ulcers and reflux esophagitis. It can be used clinically in combination with bismuth and 2 antibiotics to treat H. pylori infection, known as quadruple therapy. If eplazole is used alone to treat duodenal ulcer and reflux esophagitis, a C13 or C14 breath test can be done 2 weeks after stopping the drug. If you are taking eplazole quadruple bypass, because H. pylori is suppressed during or shortly after stopping the medication, false-negative results will occur, and it is usually necessary to stop taking the medication for 4 weeks, and then come back to do the C13 or C14 breath test to determine the effectiveness of the treatment. The medication should be used under the guidance of a doctor and should not be taken on its own to avoid serious consequences.