Painful gagging after thyroid puncture may be a normal phenomenon and does not require special treatment, or it may be caused by secondary infection, hematoma, etc., and patients should follow the doctor’s instructions for reasonable treatment. Thyroid puncture is an invasive operation, during the puncture may cause damage to local tissues or nerves, which may lead to the symptoms of gagging pain after puncture, which is a normal phenomenon, generally do not need special treatment. This is normal and generally does not require special treatment. Most patients will experience a gradual reduction in pain as the wound heals. Painful gagging after puncture may also be caused by secondary infection due to improper operation or postoperative care. Patients should be treated with antibiotics as prescribed. Some patients may also have complications such as bleeding and hematoma after puncture, and may also have symptoms such as sore throat and dyspnea. It is recommended that patients with sore throat after thyroid nodule puncture should seek timely medical treatment and actively cooperate with doctors to take targeted treatment.