The etiology of a strong cough in bed at night may be cough variant asthma, postnasal drip syndrome, allergy, etc., which requires anti-infective, topical gargle and antihistamine treatment according to the etiology. 1. Cough variant asthma: cough symptoms can also be aggravated by increased vagal excitation at night, which can be treated with drugs such as montelukast sodium and budesonide. 2. Postnasal drip syndrome: mainly with chronic cough as the main symptom, can be aggravated at night, can use budesonide, benadryl and other drugs to treat, if necessary, surgical treatment. 3. Allergy, may also be due to allergies to mites and other allergies, producing allergic cough. At this time, timely antihistamine treatment is needed, using drugs such as loratadine. 4. Cardiac insufficiency, the existence of pulmonary stasis, after lying down at night, will lead to pulmonary stasis aggravated and cough. Need to change the body position, the use of cardiac drugs such as Glycoside C, furosemide and other diuretics treatment. There may be other causes of coughing at night. The exact cause needs to be clarified after examination, so it is recommended to consult a doctor in time and use medication under the doctor’s guidance.