LDL high 6.4mmol/L is more effective in improving lifestyle while taking statins and other medications to lower lipids in a comprehensive manner. The range of LDL is less than or equal to 3.4mmol/L, 3.4~4.1mmol/L belongs to the borderline level, more than 4.1mmol/L reaches the elevated level, which is relatively more serious. For this kind of LDL reaches 6.4mmol/L people need to actively improve the lifestyle, diet to avoid greasy and high salt, eat more fresh fruits and vegetables, quit smoking and drinking, maintain appropriate physical exercise. In addition, statins such as atorvastatin, ezetimibe, and colesevelam can be taken under doctor’s supervision. If there are contraindications to oral medications, inoculation with the PCSK9 inhibitor iloyuzumab may be considered to lower cholesterol. Patients with high LDL are advised to seek medical attention as soon as possible to avoid delays.