Long-acting antihypertensive drugs with better effects include amlodipine, perindopril, valsartan, irbesartan and so on. At present, the clinical recommendation for hypertensive patients to take long-acting antihypertensive drugs, because the long-acting antihypertensive drugs are more stable in lowering blood pressure, rarely fluctuations in blood pressure, and have a significant effect on the protection of the target organs of hypertensive patients. The most classic long-acting antihypertensive drug is amlodipine, and other drugs such as ACEI (angiotensin-converting enzyme) and ARB (angiotensin II receptor inhibitor) drugs, perindopril, valsartan, and irbesartan are also commonly used long-acting antihypertensive drugs, which can maintain the patient’s blood pressure very well. In addition, some short-acting antihypertensive drugs can also play a role in lowering blood pressure for a longer period of time after being made into extended-release tablets, such as nifedipine extended-release tablets. The use of medication should be under the guidance of a doctor and should not be used without authorization.