Hepatitis B e antigen positive is mainly caused by hepatitis B virus infection. Hepatitis B e antigen positive is a sign of the degree of replication of hepatitis B virus, and its positive test results indicate that there is a large amount of hepatitis B virus in the patient’s blood, and the hepatitis B virus replication is more active, but also has a large infectious. Hepatitis B e antigen positive indicates that the patient may have acute hepatitis B or chronic hepatitis. If acute hepatitis B patients continue to appear hepatitis B e antigen positive, it means that liver tissue damage is serious, easy to develop into chronic hepatitis and cirrhosis. The persistence of hepatitis B e antigen positivity in chronic hepatitis indicates that the disease is in an active stage. If a pregnant woman is tested positive for hepatitis B e antigen, her newborn will have a higher chance of being positive for hepatitis B e antigen after birth. It is recommended that patients with positive hepatitis B e antigen find out the cause of the disease in time and follow the doctor’s instructions for reasonable treatment.