Urine microalbumin/urine creatinine 585mg/g is commonly seen in physiological elevation such as strenuous exercise, late at night, etc., generally pay attention to rest, regular review can be; pathological conditions such as glomerulonephritis, diabetic nephropathy, etc., according to the specific causes of the need to give targeted treatment, the commonly used drugs, including prednisone acetate, cyclosporine, dagliflozin, and so on. Urine microalbumin/creatinine is normal <30mg/g, 30~300mg/g indicates micro proteinuria, >300mg/g indicates massive proteinuria. 1. Physiological conditions such as strenuous activities, late at night, eating a lot of high-protein food, etc., the body albumin can be through the glomerulus a small amount of exudate caused by a small amount of microalbuminuria. Generally, it can be recovered after resting, changing bad habits, avoiding strenuous exercise and eating light diet, but regular review is still recommended. 2. Pathological conditions such as glomerulonephritis, diabetic nephropathy, hypertension and other renal damage can occur urine microalbumin/urine creatinine increased, this time according to the situation need to improve the quantification of urinary protein, renal puncture biopsy, to clarify the condition, and follow the doctor’s advice to give the treatment of lowering urinary protein, the choice of drugs include prednisone acetate, cyclosporine, daglitazide, valdecoxib, and so on. The above medications should be used in accordance with medical advice and standardized use under the guidance of a physician, and should not be used without authorization, so as not to aggravate the condition. Urine microalbumin/urine creatinine abnormal patients are recommended to go to the nephrology department of regular hospitals in a timely manner, and follow the doctor’s instructions for standardized treatment.