Heat in the palms and feet of children may be caused by food accumulation (food that is indigested and stagnates in the stomach) that turns into heat, or yin deficiency and fire exuberance (deficiency of yin and essence in the body, resulting in hyperactivity of deficiency and fire). Children with food accumulation and heat manifest as not thinking of breastfeeding, dry mouth, fullness in the epigastrium (abdomen), burning heat in the abdomen, heat in the hands and feet, irritability, sleeplessness at night, yellow urine, foul-smelling stools or constipation. Treatment with Citrus Aurantium Conducting Stagnation Pill is to clear heat and direct stagnation, eliminate stagnation and harmonize the middle. Children with yin deficiency and fire exuberance manifested as heat in hands and feet, low-grade fever and night sweating (sweating abnormally after going to sleep and stopping after waking up), disturbed and less sleepy, dry stools, yellowish and reddish stools, etc. The treatment is Zhi Bai Di Huang Wan to clear heat and induce irritability at night. Treatment with Zhi Bai Di Huang Wan to nourish yin and reduce fire (nourish yin essence and reduce fire). Adverse effects and contraindications of the above drugs are not known. If there is any related condition, it is recommended to treat it under the guidance of a professional physician, and not to blindly use the medicine on one’s own.