Pediatric leukemia is mainly a problem due to abnormal bone marrow proliferation in children and the symptoms may manifest in the blood or in other parts of the body. The main symptoms caused are anemia, joint pain, swollen lymph nodes, physical fatigue, weakness, bleeding and fever. Abnormal bone marrow hyperplasia mainly includes decreased red blood cells, platelets, and increased or decreased white blood cells. These abnormal cell counts are the signs of childhood leukemia. A low red blood cell count leads to anemia, and patients with anemia have shortness of breath and a pale complexion. A low white blood cell count can lead to some infections, which can lead to fever in the body. A high white blood cell count is mostly an increase in abnormal tumor cells, and a low platelet count can easily lead to bleeding in the body. The symptoms can be used to determine which kind of cell problem is involved. Joint pain is mainly due to the accumulation of abnormal white blood cells on or near the bone surface and in the joints. This in turn leads to pain in the bones and joints. Enlarged lymph nodes are also a common symptom of leukemia. Some leukemia cells spread to the lymph nodes, causing them to swell. Physical fatigue and weakness are the most serious consequences of leukemia. The disease often causes children to be extremely tired, weak and sluggish. Very high numbers of white blood cells cause the blood to become too thick and the circulation of blood in small blood vessels slows down. This happens. These are the symptoms of leukemia in children.