Golden Gastrointestinal Capsules and Omeprazole can be taken at the same time, but should be used in accordance with the doctor’s instructions. Golden Gastrointestinal Capsules is composed of Dahongpao, Jinbuckwheat, Huanglian, Jiyatou, Guanzhong, Sha Ren, Yanhusuo, and Muxiang. It has the efficacy of activating blood circulation, harmonizing the stomach and relieving pain. It is used for gastric and duodenal ulcers, acute and chronic gastroenteritis, chronic colitis caused by dampness-heat stasis (accumulation of damp and heat evils to form stasis), stagnation of liver and stomach qi. Contraindications and adverse reactions to this product are not clear. Omeprazole is commonly used in the form of capsules and tablets for duodenal ulcer, reflux esophagitis, gastric ulcer, and stress ulcer. Adverse reactions can be seen as headache, dizziness, drowsiness, insomnia, diarrhea, nausea, flatulence, abdominal pain, constipation, increased serum aminotransferase, and skin rash. The drug is contraindicated in severe renal insufficiency, those who are allergic to the product, and infants and young children. The instructions for Golden Gastrointestinal Capsules and Omeprazole do not specify that the two will have drug interactions, so they can be taken together, but need to be under the guidance of a doctor to use the medication reasonably.