Hepatitis B minor tri-positive refers to positive hepatitis B surface antigen, hepatitis B e antibody and hepatitis B core antibody among the five hepatitis B tests, which can often be detected in chronic hepatitis B virus carriers without clinical symptoms. The five hepatitis B tests are serological indicators to determine the presence of hepatitis B infection in humans and consist of five parts, namely hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs), hepatitis B e antigen (HBeAg) and hepatitis B e antibody (anti-HBe), and hepatitis B core antibody (anti-HBc). HBsAg is a sign of viral infection, but is less infectious in itself, and a positive result often indicates the presence of HBsAb is a protective antibody, positive means that the body has recovered or has resistance to the virus; HBeAg is a sign of viral replication, an indicator of infectiousness; HBeAb is a sign that viral replication has stopped or decreased, the infectiousness is weaker, but it does not mean that there is absolutely no infectiousness; HBcAb indicates that it has been infected or is being infected. Hepatitis B minor tri-positive is the phenomenon of the first, fourth and fifth positive items. The former are only carriers, mostly without clinical symptoms, and do not need medication but should be regularly reviewed for liver function; chronic hepatitis B patients need antiviral treatment to delay necrosis and fibrosis of liver cells, which should be taken seriously and dealt with in a timely manner.