In addition to causing biliary colic, hidden pain and indigestion, gallstones are at greater risk of causing jaundice, bile duct suppuration, inflammation of the pancreas and even death. Long-term irritation of the bile duct wall or gallbladder wall by gallstones can cause cancer. Patients with gallbladder stones all have chronic inflammation of the gallbladder, and long-term irritation causes the gallbladder to lose its contractile function, and a small percentage can become cancerous. If the stone is blocked in the abdomen or the cystic duct, it can cause pain like cutting. If changing position or medication cannot make the stone leave the obstruction site, high pressure will be generated in the gallbladder, and the blood supply to the gallbladder wall will be reduced or stopped, so bacteria can easily enter and produce a lot of toxins, causing necrosis or even perforation of the gallbladder wall. Stimulation of the lower end of the narrowing, so that this special structure like a door destroyed, causing septic cholangitis, that will be a lifelong sequelae. Therefore, if you have gallbladder stones, you should treat them early and don’t take any chances.