Gallbladder stone removal achieves stone removal and gallbladder preservation through minimally invasive surgical means, which can avoid possible digestive symptoms after gallbladder removal and serious complications of cholecystectomy such as common bile duct injury. It is suitable for patients with asymptomatic gallbladder stones who have a strong desire for gallbladder preservation and a functional gallbladder. Outpatients also often come to consult, “Director Liu, is my case suitable for gallbladder stone preservation?” Once I understood the condition and went through the thick outpatient and emergency information, the patient had just had recurrent episodes of acute and chronic cholecystitis and could not eat greasy food. In this case, even the most basic fatty meal test to detect gallbladder function could not be done, and the gallbladder contraction function was almost gone, so I could only tell the patient with great regret: you can only do the surgery of gallbladder removal. It is really a pity for these patients that if the gallbladder had not attacked six months or a year earlier and the gallbladder was still functional, it would have been possible to save the gallbladder. Therefore, it is important to remind patients with asymptomatic gallbladder stones to understand the dangers of gallbladder stones. Because on the one hand, gallbladder stones can drain into the common bile duct and induce acute cholangitis and pancreatitis, even threatening the patient’s life. On the other hand, gallbladder stones are an important causative factor of gallbladder cancer. As gallbladder stones cause chronic inflammation of the gallbladder and long-term stimulation of the gallbladder by stones, “asymptomatic gallbladder stones” may become cancerous, and once they become malignant gallbladder cancer, they often metastasize to the liver and other organs. The average survival period is only about half a year, and the prognosis is very poor. Patients with asymptomatic gallbladder stones should have a follow-up ultrasound every 3-6 months to monitor the condition of the gallbladder and stones. If there is a strong desire for gallbladder preservation and the gallbladder is functional, cholecystectomy may be an option. If a surgical deadline has to be set for gallstone preservation, it should be the earlier the better.