Gallstones do not melt, and there are no studies or cases that prove that gallstones melt or even shrink rarely. The main reason for this is that the cholesterol or bile salts in the bile are not dissolved in the bile due to various factors and are precipitated and solidified into crystals, known as gallstones. Various factors, including infection of the gallbladder and obstruction of the bile duct, cause the bile to drain poorly and concentrate in the gallbladder, precipitating crystals. More importantly, because of the high concentration of normal bile, the crystals cannot dissolve into the normal bile, so the gallstones do not melt. However, if the gallbladder is not combined with cholecystitis and the stones are small, the treatment can be conservative for the time being and the condition can be closely monitored.