The psychological changes of lung cancer patients can be divided into three stage processes: Stage I 2-5 days, characterized by suspicion and denial (suspicion of misdiagnosis or confusion with others’ disease), fear/despair (belief of having a terminal disease, no hope of cure) self-blame, guilt (especially for smoking patients). Phase II 6-14 days, characterized by anxiety, depression, nervousness, irritability, insomnia, lack of concentration, disruption of daily living skills; Phase III duration: >14 days or extended over several months, the adaptation period, usually in the middle of treatment. It is characterized by the beginning of facing up to the disease, adapting to the current situation, finding reasons for optimism, and beginning to actively cooperate with treatment. The third stage requires attention to the negative psychology that patients may develop: lack of confidence in the treatment, great fluctuation of emotions with the effect of the treatment, worry about whether the disease can be cured, and over-sensitivity to symptoms. How can family members cooperate with treatment? Patients with lung cancer desperately need the care of family members. Close and harmonious family relationship and positive and meticulous affectionate care are powerful “medicines” to help patients overcome cancer. Family members should actively guide patients, help patients reduce mental stress, strengthen patients’ will, patiently care for patients, strengthen patients’ nutritional status, assist patients who can get up and move around to walk indoors and outdoors, and encourage patients with successful treatment cases. Should we hide or tell patients about their lung cancer disease? This is a question that many family members feel troubled by. As a matter of fact, as treatment progresses, it is impossible to hide the disease completely. In fact, it is more helpful for the patient to be informed to implement the treatment and recovery plan, but it is necessary to pay attention to the right time to inform the patient.