In people’s mind, liver cysts are tumors that grow on top of the liver, and even though most of them are asymptomatic, they still make people put their mind at ease. Can liver cysts turn into liver cancer? Most of the liver cysts are benign lesions of the liver, a kind of congenital liver cysts, or can be caused by degenerative lesions of the liver. Most of them are found to be cystic enlargement in the liver during physical examination. After ruling out tumors, liver parasitic diseases, and inflammatory conditions causing cystic swelling of the liver, no treatment is needed if there is no discomfort. Usually the cyst is just some clear liquid inside, and small liver cysts are rarely connected with larger bile ducts, so even if they rupture and the liquid flows into the abdominal cavity, it has no effect on the human body. Moreover, cysts are generally not cancerous, do not damage liver function, and do not affect normal life, and there is no need to take medicine to treat them because there is no special medicine to eliminate them. Liver cysts are usually asymptomatic. When the cyst grows to a certain extent, it may press on the gastrointestinal tract and cause symptoms, such as epigastric discomfort and fullness; there are also abdominal pain and fever due to bacterial infection secondary to the cyst. The common complications of liver cysts are rupture and bleeding, bacterial infection, etc. When it exceeds 5 cm in diameter, it is called a large liver cyst. Large liver cysts tend to cause compression symptoms, and large liver cysts with symptoms are best treated surgically, as conservative treatments such as puncture and aspiration are usually prone to recur in the short term. Polycystic hepatomas should often be treated non-surgically, and because the lesions involve the entire liver, only a liver transplant can cure the disease. However, once the polycystic liver affects the respiratory circulation due to the compression of the chest and abdomen by the hepatomegaly, surgery needs to be considered to reduce the pressure. The following surgical methods can be used according to the specific conditions: 1) hepatectomy; 2) cystectomy; 3) cystotomy or major cystectomy. Currently, most of the liver cysts requiring surgery are treated by minimally invasive surgery – laparoscopic liver cyst windowing or resection.